Mr SSU-YU CHEN1,2, Dr ARUNIMA JAIN1,2, Dr MARIA MAAWAD1, Dr CANDICE KHOR1, Professor ZOLTAN ENDRE1,2, Dr JONATHAN ERLICH1,2
1Prince of Wales Hospital, Sydney , Australia, 2University of New South Wales , Sydney , Australia
Biography:
Ssu-yu (Steven) Chen is a junior doctor graduated from University of New South Wales. He has a strong academic interest in internal medicine and nephrology
Aim:
To improve our understanding of acute kidney injury (AKI) management and outcomes in patients aged ≥80 compared to patients aged 65-79 years.
Background:
Hospitalisations for AKI are increasingly common, and contribute to significant morbidity and mortality. There are limited data to guide decision-making regarding short-term dialysis in older patients.
Methods:
This retrospective single-centre study included patients aged ≥65 years who were referred to Nephrology for AKI management between February 2021 and July 2023. Patients were stratified into two groups, age 65-79 and ≥80 years. Patient characteristics and outcomes were reviewed during hospital admission and 1-year post-discharge. Primary outcome was in-hospital mortality, with secondary outcomes including need for dialysis and 1-year mortality. Data were analysed using t-tests, non-parametric tests, or Fisher’s Exact test; with significance defined as p<0.05.
Results:
Of the 157 participants, 95 were between age 65-79 years and 62 were ≥80 years. Patients aged 65-79 had lower rates of hypertension (63% vs 81%, p<0.02), with similar rates of cardiovascular and kidney disease. Patients aged 65-79 had higher rates of dialysis (17% vs 5%, p<0.03) and Intensive Care admission (32% vs 15%, p<0.02) during their AKI admission compared to those aged ≥80 years. AKI stage and length of stay were similar between groups. Mortality rates during the initial AKI admission were comparable (19% in patients aged 65-79 vs 21% aged ≥80 years, p=0.76). Of the participants who were discharged (n=126), 1-year mortality rates were similar when comparing groups (20%, p= 0.90).
Conclusion:
These data summarise current practice patterns at a single-centre and suggest similar in-hospital and 1-year mortality rates in patients with AKI aged 65-79 vs ≥80 years, highlighting the need for individualised management.