THE EFFECT OF INTRAVENOUS ESSENTIAL AMINO ACID SUPPLEMENTATION ON RECOVERY OF KIDNEY FUNCTION IN ACUTE KIDNEY INJURY PATIENTS AT DR. MOHAMMAD HOESIN GENERAL HOSPITAL, PALEMBANG
Syahpri Putra Wangsa1,2,3, Novadian Suhaimi1,2,3, Yulianto Kusnadi2,3,4, Zulkhair Ali1,2,3, Ian Effendi1,2,3, Suprapti Slamet1,2,3, Kiagus Muhammad Yusuf Arief Akbar1,2,3, Herleni Kartika1,2,3, Deddy Primadona Mulia1,2,3, Elfiani Elfiani1,2,3, Novandra Abdillah1,2,3, Rery Tri Ferri Yuniarti1,2,3, Maya Sari2,3, Chairil Dr1,2,3, Edy Nur Rachman1,2,31Department of Nephrology and Hypertension, Mohammad Hoesin General Hospital, Palembang, South Sumatera, Indonesia2Department of Internal Medicine, Palembang, South Sumatera, Indonesia3Faculty of Medicine, Sriwijaya University, Palembang, South Sumatera, Indonesia4Department of Metabolic Endocrin, Mohammad Hoesin General Hospital, Palembang, South Sumatera, Indonesia
Abstract
Aim: To determine the effect of intravenous essential amino acid supplementation on the recovery of kidney function in acute kidney injury patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Background: Acute kidney injury (AKI) is a clinical condition characterized by a rapid decline in kidney function that causes homeostatic failure in regulating fluid, electrolyte, and acid-base balance within hours to days. Nutritional supplementation is
effective in replacing lost protein and as an energy reserve.
Methods: This study is an open clinical trial of experimental research. A total of 34 research subjects participated in this study, where the subjects were grouped into treatment (IV amino acid supplementation) and placebo groups. Data analysis was
carried out using STATA in univariate and bivariate.
Results: Administration of amino acid supplements can reduce creatinine by 1.36. Meanwhile, the placebo was unable to reduce creatinine levels and even caused an increase in creatinine by 0.26.
Conclusion: Intravenous administration of essential amino acid supplements has an effect on the recovery of kidney function in acute kidney injury patients at Dr. Mohammad Hoesin General Hospital, Palembang, Indonesia.
Keywords: Acute kidney injury, Creatinine, Efficacy, Amino acid supplements
Biography
I am a Trainee Nephrologist (41 years old) of Department Nephrology and Hypertension and Department of Internal Medicine, Mohammad Hoesin General Hospital, Faculty of Medicine, Sriwijaya University, Palembang, South Sumatera, Indonesia