A SYSTEMATIC DELPHI PRIORITISATION PROCESS ON SYNTHESISED EVIDENCE INFORMING CLINICAL CARE IN PERITONEAL DIALYSIS
Brydee Cashmore1 1The University Of Sydney, Sydney, NSW, Australia
Abstract
Aim
CARI Guidelines and Cochrane Kidney Transplant aimed to systematically map all guideline recommendations and ongoing clinical trials to identify important topics required for updated evidence in peritoneal dialysis (PD) to inform clinical care and ensure efficient resource distribution.
Background
Translating new scientific evidence into clinical practice has been challenged by the rapid proliferation of scientific literature and limited resources leading to outdated clinical guidelines and systematic reviews, both of which form the backbone for clinical recommendations informing patient care. A clinician-consumer prioritisation process is required to identify the kidney communities’ priorities to maximise the impact of resources informing clinical care.
Methods
We mapped all clinical questions in PD clinical practice guidelines and Cochrane systematic reviews to develop a broad list of topics to be used in an international online Delphi prioritisation process to update work plans. We used descriptive statistics to describe the clinical questions and their mapping to high-quality systematic reviews and clinical practice guidelines.
Results
We identified 62 intervention questions from previous PD Guidelines, linked to 49 relevant Cochrane reviews and 142 ongoing clinical trials. This resulted in 18 broad PD topics used in the pilot Delphi survey with relevant stakeholders, who also had the opportunity to add other topics. This mapping process has provided viable methods that will be used for the other kidney disease domains.
Conclusion
This unique and systematic multi-stakeholder prioritisation process is feasible and will identify the currency of high-quality systematic reviews and guidelines and clinician-consumer priorities. Ensuring that limited resources are efficiently used for maximal impact and to inform clinical care.