ZAIRULLAH MIGHFAZA1, AYUDYAH NURANI1, ARWEDI ARWANTO1, LESTARININGSIH LESTARININGSIH1, SHOFA CHASANI1, DWI LESTARI PARTININGRUM1
1Division of Nephrology and Hypertension, Departement of Internal Medicine, Medical Faculty of Universitas Diponegoro/Kariadi Hospital Semarang, Semarang, Indonesia
Aim: To determine the difference in pre-transplant Human Leukocyte Antigen (HLA) matching and renal resistive index (RI) between patients with delayed graft function (DGF) and without DGF.
Background: Delayed graft function (DGF) is a major complication of kidney transplantation. It causes high rates of morbidity and determines poor graft functional outcomes. Pre-transplant HLA mathcing and RI are important early predictive factors for the development of DGF in kidney transplantation.
Methods: We analysed pre-transplant HLA matching and RI in 24 patients who underwent kidney transplantation, then we determined the difference in HLA-matching and renal resistive index between patients who developed DGF and non-DGF.
Results: There was no significant difference of number HLA matching (6,5 vs 8,2;MD -1,7 95% CI MD -6,1 to 2,71 p=0,433) between patients with DGF and without DGF. However, there was a significant difference of renal resistive index (0,75 vs 0,62;MD 0,13 95% CI MD 0,06 to 0,2 p=0,001) between patients with DGF than without DGF.
Conclusions: Renal resistive index is higher in kidney transplant patient with DGF than without DGF
Keywords: Delayed graft function, renal resistive index, Human Leukocyte antigen
Biography:
Born in Yogyakarta, Mighfaza was completed his education as a specialist in internal medicine at the Medical Faculty of Universitas Diponegoro in 2019. He is a medical staff and currently undergoing a trainee program at the Division of Nephrology and Hypertension, Medical Faculty of Universitas Diponegoro/Kariadi Hospital. He is also an active member of the Indonesian Doctors Association, the Indonesian Society of Internal Medicine, and the Indonesian Society of Nephrology.