Dr Kiagus Muhammad Yusuf Arief Akbar1,2, Dr, dr ZULKHAIR ALI1, Dr, dr TAUFIK INDRAJAYA1, dr IAN EFFENDI1,2, dr NOVADIAN SUHAIMI1, dr SUPRAPTI SLAMET1, dr DEDDY PRIMADONA MULIA1, dr HERLENI KARTIKA1, dr SYAHPRI PUTRA WANGSA1
1Mohammad Hoesin General Hospital, Palembang, Indonesia, 2Siti Khadijah Islamic Hospital, Palembang, Indonesia
Aim of this study was to determine the relationship between body mass index (BMI) and carotid intima-media thickness (CIMT) in CKD patients undergoing chronic haemodialysis.
Background. The CIMT is a sign of calcification in the blood vessels and prognostic factor for the occurrence of cardiovascular disease (CVD) in patients with chronic kidney disease (CKD), especially those who have long undergoing haemodialysis (HD). Risk factors for cardiovascular disease will also increase in patients who are overweight or obese. However, there are also CKD patients who are undergoing HD who have normal weight or underweight but still have cardiovascular disease.
Methods. This study used a cross-sectional correlation test which was carried out in the internal medicine ward at Mohammad Hoesin General Hospital Palembang in July-December 2019. The study population was all CKD patients who had undergone HD ≥3 months with age >18 years old. All subjects were examined BMI measurements after HD and CIMT measurements using doppler ultrasonography by a cardiologist consultant.
Results. There were 86 eligible chronic HD patients. Mean BMI was 21.92±3.59(kg/m2) with distribution patients underweight; 13 (15.1%), normal weight; 41 (47.7%), overweight; 21 (24.4%) and obesity; 11 (12.8%). Based on the measurement of CIMT, 32 patients (37.2%) who had severe, 26 patients (30.2%) mild-moderate and 28 patients (32.6%) normal with a median of 1 (0.5-1.89) [(mm)]. The Spearman correlation analysis showed that BMI has a significant correlation with CIMT (p=0.026, r=0.240, relative risk (RR)=3.556).
Conclusion. There is a significant relationship between BMI and CIMT in chronic HD patients. So that patients with overweight and obese have a high risk for the occurrence of vascular calcification in chronic haemodialysis patients
Keywords: BMI, CIMT, CKD, Haemodialysis
Biography:
I am a Trainee of Nephrology and Hypertension Division at Internal Medicine Department, Faculty of Medicine Sriwijaya University/Mohammad Hoesin General Hospital, Palembang, South Sumatra, Indonesia